GO:0050700 molecular_function CARD domain binding
| PAG Title | GO:0050700 molecular_function CARD domain binding |
| PAG ID | TAX026531 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | Interacting selectively and non-covalently with a CARD (N-terminal caspase recruitment) domain, a protein-protein interaction domain that belongs to the death domain-fold superfamily. These protein molecule families are similar in structure with each consisting of six or seven anti-parallel alpha-helices that form highly specific homophilic interactions between signaling partners. CARD exists in the N-terminal prodomains of several caspases and in apoptosis-regulatory proteins and mediates the assembly of CARD-containing proteins that participate in activation or suppression of CARD carrying members of the caspase family. |
| Species | Homo sapiens |
| Quality Metric Scores | nCoCo Score: 448 |
| Information Content | Rich |
| Other IDs | GO:0050700 |
| Base PAG ID | TAX026531 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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